Socioeconomic Inequities in Preemptive Kidney Transplantation and Graft Survival: An Innovative Approach to Identifying Disparities in Kidney Transplantation
2024

Socioeconomic Inequities in Kidney Transplantation

Sample size: 1975 publication 10 minutes Evidence: moderate

Author Information

Author(s): Kizilbash Sarah MD, Wi Chung-II MD, Roy Madison MS, Ryu Euijung PhD, Matas Arthur MD, Garovic Vesna MD, PhD, Riad Samy MD, MS, Schinstock Carrie MD, Juhn Young MD

Primary Institution: University of Minnesota

Hypothesis

Lower socioeconomic status (SES) recipients will have fewer preemptive transplants, longer pretransplant dialysis duration, and increased hazards of graft loss.

Conclusion

The study found significant socioeconomic disparities in kidney transplant access, dialysis duration, and graft survival, suggesting that the HOUSES index can help identify individuals at risk.

Supporting Evidence

  • Lower SES recipients had a decreased likelihood of receiving preemptive transplants.
  • Lower SES was associated with longer pretransplant dialysis duration.
  • Lower SES recipients experienced higher death-censored graft loss.

Takeaway

People with less money and resources have a harder time getting kidney transplants and keeping their new kidneys healthy.

Methodology

The study used mixed-effects multivariable logistic and Cox models to analyze data from kidney transplant recipients in Minnesota between 2010 and 2020.

Potential Biases

Potential misclassification bias due to reliance on address-based SES measures.

Limitations

The study is retrospective and may not account for unknown confounders; it also had a higher proportion of non-Hispanic White patients, limiting generalizability.

Participant Demographics

Mean age at transplant was 51.7 years; 60.6% were men, and 76.6% were White.

Statistical Information

P-Value

0.03

Confidence Interval

0.57-0.97

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1097/TXD.0000000000001734

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