Depression in mothers of children with thalassemia or blood malignancies: a study from Iran
2006

Depression in Mothers of Children with Thalassemia or Blood Malignancies

Sample size: 294 publication Evidence: moderate

Author Information

Author(s): Sharghi Afshan, Karbakhsh Mojgan, Nabaei Behrooz, Meysamie Alipasha, Farrokhi AliReza

Primary Institution: Tehran University of Medical Sciences

Hypothesis

Do mothers of children with thalassemia or blood malignancies have higher scores of depression compared with a group of control mothers?

Conclusion

Mothers of children with thalassemia or blood malignancies have significantly higher depression scores than control mothers.

Supporting Evidence

  • 46.3% of all mothers had BDI scores higher than 18.
  • 56.7% of mothers of children with malignancies had BDI scores higher than 18.
  • 51% of mothers of thalassemic children had BDI scores higher than 18.
  • 31.4% of control mothers had BDI scores higher than 18.
  • The mean BDI score for mothers of thalassemic children was 17.9.
  • The mean BDI score for mothers of children with blood malignancies was 20.
  • The mean BDI score for control mothers was 13.81.

Takeaway

Moms of kids with serious health issues often feel very sad and stressed, more than moms whose kids are healthy.

Methodology

Cross-sectional study using Beck Depression Inventory to assess depression scores in three groups of mothers.

Potential Biases

Potential bias due to the selection of hospital-based controls.

Limitations

The study used hospital-based controls, which may not represent the general population.

Participant Demographics

Mothers of children aged <15, divided into three groups: thalassemia, blood malignancies, and control.

Statistical Information

P-Value

0.001

Confidence Interval

95% CI = 1.16–4.0 for thalassemia, 95% CI = 1.48–4.99 for blood malignancies

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1745-0179-2-27

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