Wound Healing Activity of Topical Application Forms Based on Ayurveda
2011

Wound Healing Activity of Ayurvedic Topical Applications

Sample size: 36 publication 10 minutes Evidence: moderate

Author Information

Author(s): Hema Sharma Datta, Mitra Shankar Kumar, Patwardhan Bhushan

Primary Institution: Interdisciplinary School of Health Sciences, University of Pune

Hypothesis

Can Ayurvedic topical formulations improve wound healing and skin regeneration?

Conclusion

The formulations containing Yashada bhasma, Shorea robusta resin, and flax seed oil significantly improved wound contraction, collagen content, and skin breaking strength compared to the control group.

Supporting Evidence

  • The formulations showed significantly better wound contraction compared to the control group.
  • Higher collagen content was observed in the treatment groups.
  • Skin breaking strength was significantly greater in the groups treated with specific formulations.

Takeaway

This study tested creams made from traditional Indian ingredients to see if they help heal wounds better. Some creams worked really well!

Methodology

The study used excision and incision wound healing animal models to evaluate the efficacy of five topical formulations.

Potential Biases

Potential bias in the selection of formulations based on traditional knowledge without extensive modern validation.

Limitations

The study did not evaluate the long-term effects of the formulations or their safety in humans.

Participant Demographics

Swiss Wistar rats, weighing 275–325 g.

Statistical Information

P-Value

p<0.01, p<0.05

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1093/ecam/nep015

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