Case Report on Congenital Insensitivity to Pain and Anhidrosis
Author Information
Author(s): Sasnur Ashok H, Sasnur Prakash A, Ghaus-ul Raza, Shamikh Muneer
Primary Institution: Al Ameen Medical College and Hospital
Hypothesis
Congenital insensitivity to pain and anhidrosis (CIPA) is a rare disorder that affects pain and temperature perception due to genetic factors.
Conclusion
The case highlights the challenges and complications associated with CIPA, including nonunion of fractures and the progression from pain insensitivity to painful conditions.
Supporting Evidence
- CIPA is characterized by a lack of pain and temperature perception due to genetic defects.
- The incidence of CIPA is estimated to be 1 in 25,000.
- Patients often experience complications such as nonunion of fractures and infections.
- Both siblings exhibited symptoms of pain insensitivity and anhidrosis.
- Treatment complications include infection and failure of fixation.
Takeaway
This study talks about two siblings who can't feel pain, which can lead to serious injuries and complications.
Methodology
Clinical examination and radiographic assessment of the patients.
Limitations
Genetic tests were not conducted to confirm the diagnosis.
Participant Demographics
A 9-year-old girl and her 7-year-old male sibling.
Digital Object Identifier (DOI)
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