Link Between C-Reactive Protein and Carotid Atherosclerosis in CABG Candidates
Author Information
Author(s): Shakouri Parvin, Nezami Nariman, Tarzamni Mohammad Kazem, Rashid Reza Javad
Primary Institution: Tabriz University of Medical Sciences
Hypothesis
What is the relationship between High Sensitivity C-Reactive Protein (hsCRP) and Common Carotid Intima-Media Thickness (CCIMT) in patients who are candidates for Coronary Artery Bypass Grafting (CABG)?
Conclusion
Patients with common carotid artery stenosis had higher levels of serum hsCRP than patients without stenosis.
Supporting Evidence
- Participants with common carotid artery stenosis had higher levels of serum hsCRP than those without stenosis.
- There was no significant correlation between serum hsCRP level and CCIMT in patients without carotid stenosis.
- The mean age of participants was 62.71 years.
Takeaway
The study looked at patients needing heart surgery and found that those with blocked arteries had higher levels of a certain protein in their blood, but this protein didn't relate to the thickness of their artery walls if they didn't have blockages.
Methodology
Patients were evaluated using high-resolution B-mode ultrasonography and serum hsCRP levels were measured with an enzyme-linked immunosorbent assay.
Limitations
The study had a limited population size.
Participant Demographics
Mean age was 62.71 years, with a male to female ratio of 1.63.
Statistical Information
P-Value
0.009
Statistical Significance
p=0.009
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website