Neurochemical and Neuropharmacological Aspects of Circadian Disruptions
Author Information
Author(s): Kohyama Jun
Primary Institution: Tokyo Bay Urayasu/Ichikawa Medical Center
Hypothesis
Asynchronization explains the pathophysiology of insomnia and hypersomnia in adolescents.
Conclusion
The review introduces asynchronization as a clinical concept to address circadian rhythm disruptions in adolescents.
Supporting Evidence
- Approximately one quarter of junior high school students in Japan suffer from insomnia.
- Delayed bedtimes result in sleep loss and daytime sleepiness.
- Light exposure at night disrupts the biological clock and decreases melatonin secretion.
Takeaway
Some kids have trouble sleeping because their body clocks are out of sync with their daily lives, and this can make them feel tired during the day.
Methodology
The review provides an overview of neurochemical and neuropharmacological aspects of sleep and circadian rhythm regulation.
Limitations
The study does not provide specific experimental data or sample sizes.
Participant Demographics
The review discusses adolescents, particularly in Japan, China, the United States, and Spain.
Digital Object Identifier (DOI)
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