Assessing Hepatitis C in Hemodialysis Patients in Brazil
Author Information
Author(s): Engel Maricea, Malta Fernanda M, Gomes Michele MS, Mello Isabel MVGC, Pinho João RR, Ono-Nita Suzane K, Carrilho Flair J
Primary Institution: University of São Paulo, School of Medicine
Hypothesis
Chronic hemodialysis patients are at higher risk for acquiring hepatitis C virus (HCV) and the study aims to analyze the follow-up of newly acquired acute hepatitis C cases.
Conclusion
The measures taken significantly contributed to restraining the appearance of new cases of acute hepatitis C in the hemodialysis center.
Supporting Evidence
- 32 new cases of acute hepatitis C were identified during the study period.
- Blood screening showed variable ALT levels preceding anti-HCV seroconversion.
- Ten out of 32 patients received treatment with pegylated interferon for 24 weeks.
Takeaway
Patients on dialysis can get hepatitis C, and by checking their blood regularly and following strict cleaning rules, we can help stop new infections.
Methodology
Patients were tested monthly for anti-HCV and ALT levels, with positive results confirmed by HCV RNA testing.
Limitations
The study was limited to a single hemodialysis unit and may not be generalizable to other settings.
Participant Demographics
Chronic hemodialysis patients in a single center in Pato Branco, Brazil.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website