Effect of Injected Volume on VUR Correction with Dextranomer/Hyaluronic Acid
Author Information
Author(s): Dave Sumit, Darius J. Bägli
Primary Institution: Children's Hospital, University of Western Ontario
Hypothesis
Does the volume of injected dextranomer/hyaluronic acid copolymer affect the success rates of vesicoureteric reflux correction?
Conclusion
Higher injected volumes of dextranomer/hyaluronic acid are associated with improved success rates in correcting vesicoureteric reflux.
Supporting Evidence
- Success rate after 1 injection was 50% by patient and 59.2% by ureter.
- Mean injected volume was 0.9 ± 0.27 mL in successful cases versus 0.67 ± 0.24 mL in failures.
- Success after 1 injection was 78.9% using ≥0.8 mL compared to 31.7% with <0.8 mL.
Takeaway
Using more of the special gel can help fix a problem with the bladder better, but it's important to use the right amount.
Methodology
Retrospective review of patients who underwent injection for vesicoureteric reflux, analyzing various factors associated with success.
Potential Biases
Potential biases due to non-standardized injection techniques and varying definitions of success.
Limitations
The study is a nonrandomized retrospective review, which may not account for all confounding variables.
Participant Demographics
Patients with primary vesicoureteric reflux, including various grades of reflux.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website