Bone Density and Osteoporosis in Vietnamese Adults
Author Information
Author(s): Ho-Pham Lan T, Nguyen Uyen D, Pham Hoa N, Nguyen Nguyen D, Nguyen Tuan V
Primary Institution: Pham Ngoc Thach University of Medicine
Hypothesis
There is considerable discrepancy in the diagnosis of osteoporosis between reference data derived from the local population and reference data provided by densitometers.
Conclusion
The T-scores provided by the Hologic QDR4500 over-diagnosed osteoporosis in Vietnamese men and women.
Supporting Evidence
- The prevalence of osteoporosis was found to be 29% in post-menopausal women using local T-scores.
- Using the densitometer's T-scores, the prevalence of osteoporosis in women was 44%.
- In men aged 50+, the prevalence of osteoporosis was 10% based on local T-scores compared to 30% using the densitometer's T-scores.
Takeaway
This study looked at how bone density affects the diagnosis of osteoporosis in Vietnamese people, finding that many were wrongly diagnosed.
Methodology
A cross-sectional study measuring bone mineral density in 357 men and 870 women using DXA.
Potential Biases
Potential bias due to exclusion of individuals with diseases affecting bone metabolism.
Limitations
The study's findings may not be generalizable to rural populations and could underestimate the prevalence of osteoporosis.
Participant Demographics
Participants included 357 men and 870 women aged 18 to 89 years, with 58.5% of men and 51% of women aged 50 or older.
Statistical Information
P-Value
p<0.0001
Confidence Interval
95% CI: 19 - 24 for women, 95% CI: 24 - 29 for men
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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