Metabolic Profile of Offspring from Diabetic Wistar Rats Treated with Mentha piperita (Peppermint)
2011

Effects of Peppermint Juice on Offspring of Diabetic Rats

Sample size: 60 publication Evidence: moderate

Author Information

Author(s): Sandra M. Barbalho, Débora C. Damasceno, Ana Paula Machado Spada, Vanessa Sellis da Silva, Karla Aparecida Martuchi, Marie Oshiiwa, Flávia M. V. Farinazzi, Claudemir Gregório Mendes

Primary Institution: UNIMAR

Hypothesis

The study aimed to evaluate the glycemia and lipid profile of offspring from diabetic Wistar rats treated with Mentha piperita (peppermint) juice.

Conclusion

Offspring from diabetic dams treated with peppermint showed significantly reduced levels of glucose, cholesterol, LDL-c, and triglycerides, and a significant increase in HDL-c levels.

Supporting Evidence

  • Offspring from diabetic dams treated with peppermint juice had lower glucose and lipid levels.
  • Peppermint juice positively influenced the concentration of plasma lipids.
  • Significant reductions in glycemia and lipid levels were observed in treated offspring.

Takeaway

This study found that giving peppermint juice to baby rats whose mothers had diabetes helped lower their blood sugar and fat levels.

Methodology

The study involved treating offspring from diabetic and nondiabetic Wistar rats with peppermint juice for 30 days and analyzing their glycemia and lipid profiles.

Limitations

Further studies are needed to evaluate the effects on humans and determine ideal doses.

Participant Demographics

Male offspring from diabetic and nondiabetic Wistar rats.

Statistical Information

P-Value

<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2011/430237

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