Effect of ω-3 Fatty Acid on Gastrointestinal Motility after Abdominal Operation in Rats
2011
Effect of Omega-3 Fatty Acid on Gut Movement After Surgery in Rats
Sample size: 54
publication
Evidence: moderate
Author Information
Author(s): Zhang Qun, Yu Jian-Chun, Kang Wei-Ming, Zhu Guang-Jin
Primary Institution: Peking Union Medical College Hospital
Hypothesis
Can omega-3 fatty acid stimulate gastrointestinal motility after abdominal operation?
Conclusion
Omega-3 fatty acid can speed up the recovery of gut movement after surgery in rats by reducing inflammation.
Supporting Evidence
- On postoperative day 3, the gastric emptying and small bowel propulsion rates were higher in the omega-3 group compared to the other groups.
- Serum levels of inflammatory markers were lower in the omega-3 group than in the normal saline and intralipid groups.
Takeaway
Giving omega-3 fatty acids to rats after surgery helps their tummies work better and feel less sore.
Methodology
Wistar rats were divided into three groups and given different treatments after surgery, with measurements taken on postoperative days 1, 3, and 6.
Participant Demographics
Wistar rats, average body weight 250 ± 20 g.
Statistical Information
P-Value
<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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