Depression and Pesticide Exposures among Private Pesticide Applicators Enrolled in the Agricultural Health Study
2008

Depression and Pesticide Exposure in Farmers

Sample size: 17585 publication 10 minutes Evidence: moderate

Author Information

Author(s): Cheryl L. Beseler, Lorann Stallones, Jane A. Hoppin, Michael C.R. Alavanja, Aaron Blair, Thomas Keefe, Freya Kamel

Primary Institution: National Institute of Environmental Health Sciences

Hypothesis

Is there a relationship between diagnosed depression and pesticide exposure among private pesticide applicators?

Conclusion

Both acute high-intensity and cumulative pesticide exposure may contribute to depression in pesticide applicators.

Supporting Evidence

  • 3.0% of the study population reported a physician-diagnosed depression.
  • Those with a history of pesticide poisoning had significantly higher odds of depression.
  • High cumulative pesticide exposure was significantly associated with diagnosed depression.

Takeaway

Farmers who use pesticides might feel sad or depressed more often, especially if they've had a bad experience with pesticides.

Methodology

Logistic regression analyses were performed relating pesticide exposure to depression using data from private pesticide applicators.

Potential Biases

Potential bias due to self-reporting and the exclusion of certain demographics.

Limitations

The study relied on self-reported data for both depression and pesticide exposure, which may lead to misclassification.

Participant Demographics

Participants were primarily male private pesticide applicators from Iowa and North Carolina.

Statistical Information

P-Value

p<0.0001

Confidence Interval

95% CI, 1.74–3.79

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1289/ehp.11091

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