VEGF and Nitric Oxide Levels in Gastric Cancer Patients
Author Information
Author(s): Eroğlu A, Demirci S, Ayyildiz A, Kocaoğlu H, Akbulut H, Akgül H, Elhan H A
Primary Institution: Ankara University Medical School
Hypothesis
There is a correlation between serum levels of VEGF and nitric oxide in patients with gastric cancer.
Conclusion
The study found that higher tumor burden in gastric cancer patients is associated with increased levels of VEGF165 and nitric oxide.
Supporting Evidence
- The study included 11 healthy individuals and 37 gastric cancer patients.
- VEGF165 levels were significantly different across tumor stages.
- A significant relationship was found between serum nitric oxide levels and tumor stage.
Takeaway
Doctors looked at blood samples from people with stomach cancer and healthy people to see how certain substances related to cancer were different. They found that more cancer in the body means more of these substances in the blood.
Methodology
The study measured serum VEGF165 and nitric oxide levels in gastric cancer patients and healthy individuals using enzyme immunoassay and nitrite estimation.
Participant Demographics
11 healthy individuals and 37 patients with primary gastric cancer.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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