Demographic characteristics associated with a penicillin allergy label during pregnancy
2024

Demographic Factors Linked to Penicillin Allergy in Pregnant Women

Sample size: 10969 publication 10 minutes Evidence: moderate

Author Information

Author(s): Buckey Timothy M., Gleeson Patrick K., Curley Cara M., Feldman Scott F., Apter Andrea J., Fadugba Olajumoke O.

Primary Institution: Perelman School of Medicine, University of Pennsylvania

Hypothesis

What demographic characteristics are associated with having a penicillin allergy label during pregnancy?

Conclusion

Older age and atopic conditions are linked to a higher likelihood of having a penicillin allergy label, while Black race is associated with a lower likelihood.

Supporting Evidence

  • 8.6% of pregnant women in the study had a penicillin allergy label.
  • Older age groups (32-34 and 35-51 years) had higher odds of being labeled with a penicillin allergy.
  • Black race was associated with a lower likelihood of having a penicillin allergy label.

Takeaway

This study found that older pregnant women and those with conditions like asthma are more likely to be labeled as allergic to penicillin, while Black women are less likely to have this label.

Methodology

A retrospective observational study using electronic health record data from pregnant patients who had outpatient visits and delivery encounters.

Potential Biases

Potential biases in healthcare interactions and health literacy may affect the acquisition of penicillin allergy labels.

Limitations

Details of the reported penicillin reaction history were not reviewed, which may have provided insights into labeling disparities.

Participant Demographics

The study included a diverse population of pregnant women, with a significant representation of Black individuals.

Statistical Information

P-Value

p<0.0005

Statistical Significance

p<0.0005

Digital Object Identifier (DOI)

10.3389/falgy.2024.1511392

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