Rabies trend in China (1990–2007) and post-exposure prophylaxis in the Guangdong province
2008

Rabies Trends and Treatment in China (1990–2007)

Sample size: 244 publication 10 minutes Evidence: high

Author Information

Author(s): Si Han, Guo Zhong-Min, Hao Yuan-Tao, Liu Yu-Ge, Zhang Ding-Mei, Rao Shao-Qi, Lu Jia-Hai

Primary Institution: Sun Yat-Sen University

Hypothesis

What are the trends of human rabies in China from 1990 to 2007 and how can post-exposure prophylaxis be improved?

Conclusion

The failure to receive proper post-exposure prophylaxis was a major factor in the increase of human rabies cases in China.

Supporting Evidence

  • Rabies was largely under control in China from 1990 to 1996 due to vaccination campaigns.
  • The incidence of rabies cases began to rise significantly from 2001 onwards.
  • 67.2% of rabies patients did not seek medical services or receive post-exposure prophylaxis.

Takeaway

Rabies is a serious problem in China, and many people who get bitten by animals don't get the right treatment, which can lead to more cases of rabies.

Methodology

Analysis of epidemiological data for 22,527 human rabies cases and detailed medical records of 244 rabies patients in Guangdong.

Potential Biases

Potential bias in data collection from various CDCs and the lack of random sampling.

Limitations

Data may not capture the real epidemiological scenarios due to underreporting and lack of access to healthcare in remote areas.

Participant Demographics

Most patients were young, under 20 years old, with a higher incidence in males.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1186/1471-2334-8-113

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