Development of Scaffold for Ischemic Stroke Microfluidic Chip Platform
2024
Development of a Scaffold for Ischemic Stroke Microfluidic Chip Platform
publication
Author Information
Author(s): Agbomi Lidadi, Nathaniel Thomas, Goodwin Richard, Gao Bruce
Primary Institution: Clemson University
Hypothesis
A suitable 3D scaffold for cell growth is essential for modeling ischemic strokes using a microfluidic chip platform.
Conclusion
The 2% agarose hydrogel yielded the best results for creating a porous scaffold for fluid flow in ischemic stroke modeling.
Supporting Evidence
- Agarose hydrogels of different concentrations were tested for their suitability in modeling ischemic strokes.
- The 2% agarose hydrogel maintained gel-like characteristics while being more porous.
Takeaway
Scientists are making a special gel to help study strokes better, which can help doctors understand and treat them.
Methodology
3D agarose hydrogels were fabricated and tested for porosity and fluid flow characteristics.
Digital Object Identifier (DOI)
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