Diastolic time – frequency relation in the stress echo lab: filling timing and flow at different heart rates
2008

Diastolic Time and Heart Rate in Stress Echocardiography

Sample size: 161 publication 10 minutes Evidence: moderate

Author Information

Author(s): Bombardini Tonino, Gemignani Vincenzo, Bianchini Elisabetta, Venneri Lucia, Petersen Christina, Pasanisi Emilio, Pratali Lorenza, Alonso-Rodriguez David, Pianelli Mascia, Faita Francesco, Giannoni Massimo, Arpesella Giorgio, Picano Eugenio

Primary Institution: Institute of Clinical Physiology, National Council of Research, Pisa, Italy

Hypothesis

Can an operator-independent sensor accurately measure diastolic time during stress echocardiography?

Conclusion

The study demonstrates that diastolic time can be effectively monitored during stress using an acceleration force sensor, revealing significant changes associated with various cardiac conditions.

Supporting Evidence

  • Diastolic time decreased significantly during stress compared to rest.
  • At peak stress, 62 out of 161 patients showed a reversal of the systolic/diastolic ratio.
  • Diastolic filling rate increased from 101 ml/m2*s-1 at rest to 219 ml/m2*s-1 at peak stress.

Takeaway

Doctors can use a special sensor to measure how long the heart fills with blood during exercise, which helps them understand heart health better.

Methodology

The study involved 161 patients undergoing stress echocardiography, where diastolic and systolic times were recorded using a force sensor during different stress tests.

Potential Biases

Potential bias due to the exclusion of patients with unstable conditions and reliance on a single measurement method.

Limitations

The study lacked Doppler indexes for diastolic function assessment during stress, and some patients had low signal quality.

Participant Demographics

161 patients (106 males, average age 62 years) referred for stress echocardiography.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1476-7120-6-15

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