Case Report of Two Siblings with Appendiceal Cancer
Author Information
Author(s): Racek Adrianne R, Rabe Kari G, Wick Myra J, Psychogios Apostolos, Lindor Noralane M
Primary Institution: University of North Dakota Medical School
Hypothesis
Is there a hereditary factor influencing the development of appendiceal tumors in siblings?
Conclusion
The occurrence of appendiceal cancer in these siblings may be a rare coincidence rather than a hereditary syndrome.
Supporting Evidence
- Appendiceal adenocarcinoma accounts for less than 0.5% of all gastrointestinal neoplasms.
- Published accounts of familial instances of primary appendiceal tumors are strikingly rare.
- The siblings represent the first report of first-degree relatives with appendiceal adenocarcinomas.
Takeaway
This study talks about two siblings who both got a rare type of cancer in their appendix, which is very unusual.
Methodology
A retrospective chart review of appendiceal cancer cases at Mayo Clinic was conducted.
Limitations
The study is based on a small sample size and retrospective data, limiting the ability to draw broader conclusions.
Participant Demographics
Two siblings, a 69-year-old male and a 77-year-old female, both of Greek descent.
Digital Object Identifier (DOI)
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