Carotid Intima Media Thickness in Nigerians with Hypertension and Diabetes
Author Information
Author(s): Okeahialam Basil N., Alonge Benjamin A., Pam Stephen D., Puepet Fabian H.
Primary Institution: Jos University Teaching Hospital
Hypothesis
Is carotid intima media thickness (IMT) a reliable measure of cardiovascular disease burden in Nigerian Africans with hypertension and diabetes?
Conclusion
Diabetic and hypertensive Nigerians show a similar burden of cardiovascular disease risk factors, with apparently normal individuals also exhibiting significant risk.
Supporting Evidence
- Diabetics and hypertensives had similar carotid IMT values.
- Prevalence of carotid atherosclerosis was 47.5% for diabetics and 48.9% for hypertensives.
- Apparently normal subjects had a prevalence of 36.5% for carotid atherosclerosis.
Takeaway
This study looked at how thick the arteries are in people with diabetes and high blood pressure in Nigeria, finding that both groups have similar heart disease risks.
Methodology
The study involved 70 diabetic patients, 70 hypertensive patients, and 71 normal controls, all undergoing carotid ultrasonography to measure IMT.
Potential Biases
Potential bias due to the single experienced radiologist performing all measurements.
Limitations
The study did not comprehensively screen for new and emerging cardiovascular risk factors.
Participant Demographics
Participants included 70 diabetics (36 females, 34 males), 70 hypertensives (37 females, 33 males), and 71 normal controls (36 females, 35 males).
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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