Monitoring Antibiotic Resistance in Al-Karak Hospital, Jordan (2022)
Author Information
Author(s): Aqel Amin A., Al-Matarneh Tala M., Al-Tarawneh Tayf K., Alnawayseh Tahrir, Alsbou Mohammed, Gaber Yasser, Vázquez-Lago Juan Manuel, Estany-Gestal Ana, Salgado-Barreira Angel
Primary Institution: Mutah University
Hypothesis
What are the antibiotic resistance patterns in clinical specimens from Al-Karak Governmental Hospital in 2022?
Conclusion
The study found a significant prevalence of extensively drug-resistant (XDR) and pan-drug-resistant (PDR) strains, particularly in Pseudomonas aeruginosa and Klebsiella pneumoniae, highlighting the need for improved antimicrobial stewardship.
Supporting Evidence
- Enterococcus faecalis showed 100% susceptibility to nitrofurantoin.
- Escherichia coli and Klebsiella pneumoniae had high susceptibility to fosfomycin.
- Pseudomonas aeruginosa exhibited 15% of its strains as extensively drug-resistant (XDR).
- High susceptibility in several Access group antibiotics supports their use in empirical therapy.
- Resistance was notable for trimethoprim + sulfamethoxazole in E. coli and K. pneumoniae.
Takeaway
This study looked at how bacteria in a hospital in Jordan resist antibiotics, showing that some bacteria are very hard to treat, which means doctors need to be careful with how they use antibiotics.
Methodology
A cross-sectional retrospective study of bacterial species and their antimicrobial susceptibility was conducted at Al-Karak Governmental Hospital from January to December 2022, including 1187 isolates.
Potential Biases
Potential bias in data collection from a single hospital setting.
Limitations
The study may not represent all regions of Jordan due to its focus on a single hospital.
Participant Demographics
Clinical specimens from patients at Al-Karak Governmental Hospital.
Digital Object Identifier (DOI)
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