GEROSCIENCE-DRIVEN THERAPIES TO TARGET HEALTHSPAN WITH AGING: CLINICAL IMPLICATIONS
2024

Targeting Aging to Improve Healthspan

publication

Author Information

Author(s): Espinoza Sara, Gonzales Mitzi, Musi Nicolas

Primary Institution: Cedars-Sinai Medical Center

Hypothesis

By targeting aging, we may prevent or delay several age-related diseases and increase healthspan.

Conclusion

Clinical trials are needed to determine the efficacy of pharmacological interventions aimed at improving healthspan.

Supporting Evidence

  • The geroscience hypothesis suggests that targeting aging can prevent age-related diseases.
  • Clinical trials are necessary to assess the safety and efficacy of new therapies.
  • A patient-centered approach is essential for tailoring interventions.

Takeaway

Scientists think that if we can slow down aging, we can help people live healthier for longer. They are testing different medicines to see if they work.

Methodology

Clinical trials of candidate agents are underway to examine pharmacological interventions.

Potential Biases

The majority of physicians providing care to older adults may not be geriatricians, which could lead to a lack of knowledge in geroscience.

Limitations

Interventions must not worsen existing medical conditions or lead to negative side effects.

Participant Demographics

Older adults, though specific demographics are not provided.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.1910

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