Endocrine disruptor chemicals exposure and female fertility declining: from pathophysiology to epigenetic risks
2024

Endocrine Disruptor Chemicals and Female Fertility

publication Evidence: moderate

Author Information

Author(s): Tricotteaux-Zarqaoui Sophian, Lahimer Marwa, Abou Diwan Maria, Corona Aurélie, Candela Pietra, Cabry Rosalie, Bach Véronique, Khorsi-Cauet Hafida, Benkhalifa Moncef

Primary Institution: University of Picardie Jules Verne

Hypothesis

The review hypothesizes a link between environmental and professional exposure to endocrine disruptor chemicals (EDCs) and the decline in female fertility.

Conclusion

The review highlights that exposure to EDCs negatively impacts various reproductive processes in women, leading to infertility and related disorders.

Supporting Evidence

  • EDCs are linked to various reproductive disorders in women, including endometriosis and premature ovarian insufficiency.
  • Women are more exposed to EDCs than men due to higher usage of chemical products.
  • EDCs can disrupt hormonal balance, leading to infertility and poor IVF outcomes.
  • Environmental exposure to EDCs is widespread, affecting both professionals and the general population.

Takeaway

This study explains that chemicals in everyday products can harm women's ability to have babies by messing with their hormones and reproductive health.

Methodology

This is a review article summarizing existing literature on the effects of EDCs on female fertility.

Limitations

The review acknowledges variability in exposure levels and the complexity of human reproductive systems as limitations in understanding EDCs' impact.

Digital Object Identifier (DOI)

10.3389/fpubh.2024.1466967

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