Corneal Endothelial Cell Density in Normal Iranian Eyes
Author Information
Author(s): Hashemian Mohammad Nasser, Moghimi Sasan, Fard Masood Aghsaie, Fallah Mohammad Reza, Mansouri Mohammad Reza
Primary Institution: Tehran University Eye Research Center, Farabi Eye Hospital
Hypothesis
How does corneal endothelial cell density and morphology in normal Iranian eyes compare to other populations?
Conclusion
The study provides normative data for corneal endothelial cell characteristics in Iranian eyes, showing no gender differences but significant age-related changes.
Supporting Evidence
- The mean cell density was found to be 1961 ± 457 cell/mm2.
- There was a statistically significant decrease in mean cell density with age.
- The study found no significant differences in cell density between genders.
Takeaway
This study looked at the cells in the back of the eye in normal Iranian people and found that these cells change as people get older.
Methodology
Specular microscopy was performed on 525 eyes of normal Iranian individuals aged 20 to 85 years to analyze endothelial cell density and morphology.
Limitations
The study did not include individuals under 20 years of age, which limits the understanding of endothelial characteristics in younger populations.
Participant Demographics
Participants were 525 normal volunteers aged 20 to 85 years, with 271 males (51.7%) and 254 females (48.3%).
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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