Rooting the eutherian tree: the power and pitfalls of phylogenomics
2007

Rooting the Eutherian Tree: Phylogenomics Insights

Sample size: 10 publication Evidence: high

Author Information

Author(s): Nishihara Hidenori, Okada Norihiro, Hasegawa Masami

Primary Institution: Tokyo Institute of Technology

Hypothesis

Can genome-scale data accurately determine the root of the eutherian tree?

Conclusion

The separate model of phylogenetic inference is preferred over the concatenate model when analyzing genome-scale data due to significant variations in evolutionary features among genes.

Supporting Evidence

  • The separate model consistently supported the basal Afrotheria hypothesis.
  • Concatenate analysis suggested a misleading monophyly of Afrotheria and Xenarthra.
  • The study collected a large dataset of 2,789 genes to improve phylogenetic resolution.

Takeaway

Scientists studied many genes from different mammals to figure out how they are related. They found that using different methods to analyze the data can lead to different conclusions about their family tree.

Methodology

The study used maximum likelihood methods to analyze a dataset of 2,789 genes from ten mammalian species.

Potential Biases

There is a risk of systematic error in phylogenetic inference due to biases in the data.

Limitations

The study's conclusions may not be definitive due to the complexity of evolutionary relationships and potential biases in the data.

Participant Demographics

The study analyzed genomic data from ten mammalian species, including the nine-banded armadillo and the African elephant.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/gb-2007-8-9-r199

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