Epidemiological Patterns and Treatment of Idiopathic Intracranial Hypertension
Author Information
Author(s): Azzam Ahmed Y., Nassar Mahmoud, Morsy Mahmoud M., Mohamed Adham A., Wu Jin, Essibayi Muhammed Amir, Altschul David J.
Primary Institution: Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA
Hypothesis
What are the nationwide trends in the epidemiology, treatment patterns, and outcomes of Idiopathic Intracranial Hypertension in the US from 1990 to 2024?
Conclusion
The study highlights Idiopathic Intracranial Hypertension as a systemic disorder with significant metabolic implications and rising incidence rates, especially among adults.
Supporting Evidence
- Adult IIH incidence increased from 16.0 to 127.0 per 100,000 over the study period.
- Female predominance in IIH cases increased, with a female-to-male ratio of 3.29.
- Southern regions of the US showed the highest prevalence of IIH at 43.0%.
Takeaway
This study looks at how many people in the US have a condition called Idiopathic Intracranial Hypertension and how it affects them, showing that more adults are getting it and that it can be linked to other health problems.
Methodology
Retrospective analysis using the TriNetX US Collaborative Network database, assessing demographic characteristics, treatment patterns, and comorbidities.
Potential Biases
Potential coding inaccuracies and selection bias in the data.
Limitations
Dependence on electronic health records may introduce biases related to coding accuracy and data completeness; retrospective nature limits inferences regarding treatment efficacy.
Participant Demographics
Mean age of 37 years, predominantly female (85.56%), with a majority being white (59.43%).
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI: 6.71–7.17
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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