The Effects of Methylphenidate on Decision Making in Attention-Deficit/Hyperactivity Disorder
2008

Effects of Methylphenidate on Decision Making in ADHD

Sample size: 21 publication 10 minutes Evidence: moderate

Author Information

Author(s): DeVito Elise E., Blackwell Andrew D., Kent Lindsey, Ersche Karen D., Clark Luke, Salmond Claire H., Dezsery Anna Maria, Sahakian Barbara J.

Primary Institution: University of Cambridge

Hypothesis

How does methylphenidate affect decision making in children with ADHD?

Conclusion

Methylphenidate reduced risk-prone betting behavior in children with ADHD.

Supporting Evidence

  • Methylphenidate improved decision-making by reducing impulsive betting.
  • ADHD participants made more poor decisions compared to healthy controls.
  • Behavioral symptoms correlated with decision-making quality in ADHD.

Takeaway

This study looked at how a medicine called methylphenidate helps kids with ADHD make better decisions when betting. It found that the medicine made them bet more carefully.

Methodology

Twenty-one boys with ADHD participated in a double-blind, placebo-controlled trial using the Cambridge Gamble Task.

Potential Biases

Potential bias in self-reported measures and the small sample size.

Limitations

The study was limited to male participants aged 7-13 and may not generalize to females or older children.

Participant Demographics

Participants were 21 boys aged 7-13 diagnosed with ADHD.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1016/j.biopsych.2008.04.017

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