Flunarizine vs Propranolol for Pediatric Migraine Prevention
Author Information
Author(s): Muacevic Alexander, Adler John R, Vaswani ND, Lamba Preet, Arya Vandana, Lekhwani Seema
Primary Institution: Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, IND
Hypothesis
Is flunarizine as effective as propranolol in preventing pediatric migraines?
Conclusion
Flunarizine is as effective as propranolol for the prophylactic management of children with migraine.
Supporting Evidence
- Both flunarizine and propranolol achieved a 50% or more reduction in headache days in comparable proportions of patients.
- Minor adverse effects were similar in both treatment groups.
- None of the patients reported serious adverse events.
Takeaway
This study looked at two medicines to help kids with migraines. Both worked about the same to help reduce the number of headache days.
Methodology
An open-label randomized trial with parallel group assignment was conducted among patients aged 5 to 14 years with migraine.
Limitations
The study had a small sample size and did not use a placebo control.
Participant Demographics
Children aged 5 to 14 years, with 55% females.
Statistical Information
P-Value
0.752
Statistical Significance
p = 0.752
Digital Object Identifier (DOI)
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