The effects of camel milk in systemic inflammation and oxidative stress of cigarette smoke-induced chronic obstructive pulmonary disease model in rat
2024

Camel Milk's Effects on Inflammation and Oxidative Stress in COPD Rats

Sample size: 35 publication Evidence: moderate

Author Information

Author(s): Behrouz Sepide, Mohammadi Mahla, Sarir Hadi, Boskabady Mohammad Hossein

Primary Institution: Mashhad University of Medical Sciences

Hypothesis

Camel milk can reduce systemic inflammation and oxidative stress in a rat model of COPD induced by cigarette smoke.

Conclusion

Camel milk might be effective in attenuating the effects of cigarette smoke-induced systemic inflammation and oxidative stress.

Supporting Evidence

  • Total and differential WBC counts were significantly increased in CS-exposed rats.
  • Treatment with camel milk improved all measured variables compared to the COPD group.
  • The improvements with high doses of camel milk were greater than those with dexamethasone.

Takeaway

This study found that giving camel milk to rats exposed to cigarette smoke helped reduce inflammation and stress in their bodies.

Methodology

35 male Wistar rats were divided into five groups, with some receiving camel milk and others receiving dexamethasone after being exposed to cigarette smoke.

Limitations

The study did not provide pulmonary function tests or investigate higher doses of camel milk.

Participant Demographics

Male Wistar rats, weighing 200±250g.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.3389/fvets.2024.1464432

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