Cholera toxin — A foe & a friend
2011

Cholera Toxin: A Foe and a Friend

publication Evidence: high

Author Information

Author(s): Sánchez Joaquín, Holmgren Jan

Primary Institution: University of Gothenburg

Conclusion

Cholera toxin has evolved from being a harmful agent in cholera to a valuable tool in immunology and vaccine development.

Supporting Evidence

  • Cholera toxin has been shown to be a potent adjuvant in immunology.
  • The non-toxic B-subunit of cholera toxin is used in oral cholera vaccines.
  • Research indicates cholera toxin can promote immunological tolerance against certain antigens.

Takeaway

Cholera toxin can make people very sick, but scientists have found ways to use it to help create vaccines and treat diseases.

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