Variceal Band Ligation in the Prevention of Variceal Bleeding: A Multicenter Trial
2011

Preventing Variceal Bleeding with Band Ligation

Sample size: 603 publication Evidence: moderate

Author Information

Author(s): Asma Ouakaa-Kchaou, Jamel Mir, Khaoula Houda Boussourra, Nabil Ajmi, Salem Azzouz, Msaddek Abdallah, Hatem Ben Mami, Nabyl Ben Bouzaidi, Slim Chouaib, Lamia Golli, Wissem Melki, Taoufik Najjar, Hammouda Saffar, Najet Belhadj, Abdeljabbar Ghorbel

Primary Institution: Department of Gastroenterology, Habib Thameur Hospital, Tunis, Tunisia

Hypothesis

Is endoscopic band ligation effective in preventing upper gastrointestinal bleeding in patients with portal hypertension?

Conclusion

Endoscopic band ligation significantly improves the prevention of variceal bleeding, but further therapeutic options are needed.

Supporting Evidence

  • Endoscopic band ligation achieved variceal eradication in 81.6% of patients.
  • The first variceal bleeding rate after EBL was 10.2%.
  • Recurrent varices were eradicated by one to three sessions of EBL in 84.6% of cases.
  • Major complications occurred in 51 patients, primarily due to esophageal ulcers.
  • Overall, 78 patients died, with 27 deaths related to bleeding.

Takeaway

Doctors use a special band to tie off swollen veins in the throat to stop dangerous bleeding in people with liver problems.

Methodology

A multicenter trial analyzing the efficacy and side effects of endoscopic band ligation for preventing esophageal variceal bleeding.

Limitations

The study had few exclusion criteria, and a high proportion of patients had advanced liver disease.

Participant Demographics

{"age":"55 (10 – 95)","sex":{"male":332,"female":271},"indication_of_band_ligation":{"primary_prophylaxis":49,"secondary_prophylaxis":554},"etiology_of_portal_hypertension":{"cirrhosis":"91.5%","portal_cavernoma":"6.8%","nodular_regenerative_hyperplasia":"1%","congenital_hepatic_fibrosis":"0.7%"}}

Digital Object Identifier (DOI)

10.4103/1319-3767.77238

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