Efficacy of Warm and Cool Lozenges for Sore Throat Relief
Author Information
Author(s): Wade Alan G, Morris Christopher, Shephard Adrian, Crawford Gordon M, Goulder Michael A
Primary Institution: CPS Research, Glasgow, UK
Hypothesis
The study aims to determine the analgesic and sensorial benefits of two different AMC/DCBA throat lozenge formulations compared to a placebo.
Conclusion
Both AMC/DCBA Warm and Cool lozenges are effective and well-tolerated treatments for acute sore throat, providing significant relief and emotional benefits.
Supporting Evidence
- Both lozenges provided significant analgesic effects compared to the placebo.
- Patients reported feeling better and less frustrated after using the lozenges.
- The effects of the lozenges were felt as early as 1-5 minutes post dose.
Takeaway
The study tested two types of throat lozenges to see which one helps sore throats better, and both worked well!
Methodology
This was a multicentre, randomised, double-blind, single-dose study involving 225 adult patients with acute sore throat.
Limitations
The study did not investigate the sensory impact of the excipients of the two lozenge formulation variants on the placebo effect.
Participant Demographics
Predominantly Caucasian, slightly more women than men, mean age 31.7 years.
Statistical Information
P-Value
p<0.0001
Confidence Interval
95% CI: -1.27,-0.33 for Warm lozenge; -1.56,-0.60 for Cool lozenge
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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