Age- and Sex-Based Developmental Biomarkers in Eye Movements
2024

Age and Sex Differences in Eye Movements

Sample size: 23557 publication 10 minutes Evidence: high

Author Information

Author(s): Carrick Frederick Robert, Hunfalvay Melissa, Bolte Takumi, Azzolino Sergio F., Abdulrahman Mahera, Hankir Ahmed, Antonucci Matthew M., Al-Rumaihi Nouf

Primary Institution: College of Medicine, University of Central Florida

Hypothesis

How do age and sex influence eye movement characteristics in a large cohort?

Conclusion

Eye movements are sex-specific and provide normative data for comparing eye movement functions by age.

Supporting Evidence

  • Eye movements provide biomarkers for disease classification with superior accuracy.
  • Statistically significant differences were observed in eye movement functions between males and females.
  • Normative data for eye movements can help in diagnosing neurological diseases.

Takeaway

This study shows that boys and girls, as well as men and women, move their eyes differently, and understanding these differences can help doctors diagnose brain issues better.

Methodology

Participants completed six eye movement assessments, and data were analyzed using multiple t-tests and linear regression models.

Potential Biases

The study may have biases due to unequal representation of sexes in previous research.

Limitations

The study did not control for all possible conditions affecting eye movements.

Participant Demographics

Participants included 11,871 males and 11,686 females aged 6 to 80 years, with 42.38% reporting race and ethnicity.

Statistical Information

P-Value

p<0.001

Confidence Interval

95%

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/brainsci14121288

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