Improving the outcome of salvage treatment for non-seminomatous germ cell tumours (NSGCT)
2000

Improving Treatment Outcomes for Non-Seminomatous Germ Cell Tumours

Sample size: 41 publication Evidence: moderate

Author Information

Author(s): Bono J S de, Paul J, Simpson A, Anthoney A, Kirk D, Underwood M, Graham J, Kaye S B

Primary Institution: Departments of Medical Oncology, University of Glasgow

Hypothesis

The study investigates the effectiveness of salvage treatment strategies for patients with relapsed non-seminomatous germ cell tumours.

Conclusion

The study indicates an improving outlook for patients with relapsed non-seminomatous germ cell tumours, especially those treated surgically.

Supporting Evidence

  • 41 patients were treated for relapsed non-seminomatous germ cell tumours.
  • 57% of patients requiring chemotherapy remain alive.
  • 50% of patients are disease free after treatment.
  • 59% of patients treated with chemotherapy and surgery have no evaluable disease.
  • 36% of patients treated with chemotherapy alone remain alive.

Takeaway

This study looked at how well patients with a specific type of cancer did after their treatment didn't work. It found that some treatments are getting better.

Methodology

The study analyzed treatment outcomes for 41 patients with relapsed non-seminomatous germ cell tumours over a period from 1991 to 1996.

Participant Demographics

Patients treated between 1991 and 1996 for relapsed non-seminomatous germ cell tumours.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1054/bjoc.2000.1290

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