Empathy and Reversed Empathy of Stress in Mice
2011

Empathy and Reversed Empathy of Stress in Mice

Sample size: 80 publication 10 minutes Evidence: moderate

Author Information

Author(s): Watanabe Shigeru

Primary Institution: Keio University

Hypothesis

Does stress affect empathy and memory in mice?

Conclusion

Stress can enhance memory of aversive experiences, but the social context of stress influences this effect.

Supporting Evidence

  • Stress enhances memory of aversive experiences in mice.
  • Common stress experience reduces memory enhancement effects.
  • Stress with non-stressed cage mates enhances memory effects.

Takeaway

When mice experience stress together, they remember it differently than when they are alone; sometimes they remember better, and sometimes worse.

Methodology

The study used behavioral experiments with male C57/BL6 mice to assess the effects of stress on memory and empathy.

Potential Biases

Potential bias in interpreting the effects of social context on stress responses.

Limitations

The study was conducted on a specific strain of mice, which may limit generalizability.

Participant Demographics

80 male C57/BL6 mice, 8 weeks old.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0023357

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