BMI Increase After Chemotherapy in Testicular Cancer Survivors
Author Information
Author(s): Nord C, Fosså S D, Egeland T
Primary Institution: University Hospital, The Norwegian Radium Hospital (NRH), Oslo, Norway
Hypothesis
Is there an abnormal BMI increase among long-term testicular cancer survivors compared to a control group of age-matched men from the normal population?
Conclusion
Testicular cancer survivors show an abnormal increase in BMI after treatment, particularly those treated with chemotherapy at a young age.
Supporting Evidence
- Testicular cancer survivors have a higher annual BMI increase compared to controls.
- Young age at diagnosis is associated with a higher risk of abnormal BMI increase.
- Chemotherapy is an independent factor predicting high annual BMI increase.
Takeaway
Young men who survive testicular cancer might gain more weight after treatment, especially if they had chemotherapy.
Methodology
A national multicentre follow-up survey was conducted on testicular cancer survivors to assess long-term sequelae after treatment, comparing BMI before and after treatment with a control group.
Potential Biases
Potential biases may arise from differences in age and observation time between testicular cancer survivors and controls.
Limitations
The control group was older on average than the testicular cancer survivors, which may affect BMI comparisons.
Participant Demographics
Testicular cancer survivors aged 18–75 years treated between 1980 and 1994; control group consisted of age-matched men from the general population.
Statistical Information
P-Value
p=1.4×10−15
Confidence Interval
95% CI for mean
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website