The treatment of Wilms' tumour: results of the United Kingdom Children's Cancer Study Group (UKCCSG) second Wilms' tumour study
2000
Treatment of Wilms' Tumour in Children
publication
Evidence: high
Author Information
Author(s): Mitchell C, Jones P Morris, Kelsey A, Vujanic G M, Marsden B, Shannon R, Gornall P, Owens C, Taylor R, Imeson J, Middleton H, Pritchard J
Primary Institution: Paediatric Oncology, Oxford Radcliffe Hospital
Hypothesis
The study aims to refine treatment for children with Wilms' tumour and improve outcomes for various stages of the disease.
Conclusion
The majority of children with Wilms' tumour now have an excellent outlook due to refined treatment methods.
Supporting Evidence
- The 4-year event-free survival for stage I and II favourable histology patients was 94% and 91%, respectively.
- Stage III favourable histology patients had a 4-year event-free survival of 84%.
- The outlook for patients with clear cell sarcoma of the kidney is as good as for those with favourable histology.
Takeaway
Doctors are getting better at treating a type of kidney cancer in kids, which helps most of them get better.
Methodology
The study involved primary nephrectomy followed by chemotherapy and radiotherapy based on the patient's stage and histology.
Digital Object Identifier (DOI)
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