3D-printed porous titanium versus polyetheretherketone cages in lateral lumbar interbody fusion: a systematic review and meta-analysis of subsidence
2024

Comparing 3D-printed Titanium and PEEK Cages in Lumbar Fusion

Sample size: 265 publication Evidence: moderate

Author Information

Author(s): Liu Shu-Xin, Zeng Teng-Hui, Chen Chien-Min, He Li-Ru, Feng An-Ping, Jhang Shang-Wun, Lin Guang-Xun

Hypothesis

This study aims to compare the rates of cage subsidence between 3D-printed titanium and polyetheretherketone cages in lateral lumbar interbody fusion.

Conclusion

The subsidence rate associated with 3D-Ti cages in lateral lumbar interbody fusion is significantly lower than that observed with PEEK cages.

Supporting Evidence

  • The overall cage subsidence rate was significantly lower with 3D-Ti compared to PEEK.
  • 3D-Ti cages had a subsidence rate of 8.47%, while PEEK cages had a rate of 27.78%.
  • Severe subsidence was significantly reduced in the 3D-Ti group compared to the PEEK group.

Takeaway

Using 3D-printed titanium cages in spine surgery is better because they don't sink into the bone as much as plastic cages do.

Methodology

A systematic review and meta-analysis were conducted, analyzing data from three studies that compared cage subsidence rates.

Potential Biases

Potential biases due to the retrospective nature of the studies and variations in surgical techniques.

Limitations

The studies included were retrospective and had a modest sample size, lacking prospective randomized controlled trials.

Participant Demographics

Patients were primarily older adults with degenerative lumbar disease, with a mean age around 66 years.

Statistical Information

P-Value

p<0.00001

Confidence Interval

95% CI: 0.14 to 0.44

Statistical Significance

p<0.00001

Digital Object Identifier (DOI)

10.3389/fmed.2024.1389533

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