Trials and tribulations: obstacles to clinical trial recruitment
2003

Obstacles to Clinical Trial Recruitment

Sample size: 133 Editorial Evidence: moderate

Author Information

Author(s): Reed N, Siddiqui N

Primary Institution: Western Infirmary, Beatson Oncology Centre

Conclusion

The study highlights significant barriers to patient recruitment for clinical trials, particularly in areas of social deprivation and rurality.

Supporting Evidence

  • Only 68 out of 106 patients were deemed fit enough for a Platinum/Taxane combination treatment.
  • The study achieved a 29% participation rate in clinical trials, above the national average.
  • Patients from areas of high social deprivation face unique challenges in accessing clinical trials.

Takeaway

This study shows that many patients who need treatment for ovarian cancer can't join clinical trials because of various challenges, like living far away or not being healthy enough.

Methodology

The study examined patients in the Grampian region over a 3-year period who were referred for treatment of ovarian cancer.

Potential Biases

Potential biases in patient selection and treatment recommendations based on social and geographical factors.

Limitations

The study may not fully represent all populations due to geographical and social factors.

Participant Demographics

Patients from the Grampian region, including those from urban and rural areas, with a median age of 76 years for those receiving carboplatin only.

Digital Object Identifier (DOI)

10.1038/sj.bjc.6601233

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