Antimicrobial Activity of Tea and Agarwood Leaf Extracts Against Multidrug-Resistant Microbes
Author Information
Author(s): Shah Rucksana Akhter Urme, Ahmed Syeda Fahmida, Imran Md Abdus Shukur, Akhand Mst Rubaiat Nazneen, Khan Mohammad Mehedi Hasan
Primary Institution: Sylhet Agricultural University, Sylhet, Bangladesh
Hypothesis
This study aims to analyze the phytochemical constituency and antimicrobial activity of tea and agarwood leaf extracts and their combined effect against multidrug-resistant pathogens.
Conclusion
Tea and agarwood leaf extracts show promising antibacterial and antifungal activity against multidrug-resistant microbes, suggesting their potential as alternative therapeutic agents.
Supporting Evidence
- Fresh tea leaves showed the highest total phenolic content and antioxidant activity.
- Green tea exhibited the maximum zone of inhibition against Klebsiella pneumoniae.
- BT-8 extracts combined with antibiotics showed significant synergistic effects against Escherichia coli.
- Most leaf extracts demonstrated significant antimicrobial activity against selected pathogens.
- Antimicrobial activity was higher in methanol and ethanol extracts compared to chloroform extracts.
Takeaway
This study found that tea and agarwood leaves can help fight germs that are hard to treat with regular medicine, making them useful for health.
Methodology
The study involved collecting tea and agarwood leaves, extracting their phytochemicals using different solvents, and testing their antimicrobial activity against various pathogens using disc diffusion methods.
Limitations
The study's limitations include the need for broader spectrum analysis and standardization of extracts for therapeutic preparations.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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