Unusual Paraneoplastic Syndrome Accompanies Neuroendocrine Tumours of the Pancreas
2011

Unusual Paraneoplastic Syndrome with Neuroendocrine Tumours of the Pancreas

Sample size: 1 publication Evidence: low

Author Information

Author(s): Bertani Helga, Messerotti Alessandro, Di Benedetto Fabrizio, Manta Raffaele, Greco Milena, Casoni Federica, Losi Luisa, Conigliaro Rita

Primary Institution: Nuovo Ospedale Civile S. Agostino-Estense, Modena, Italy

Hypothesis

Can myasthenia gravis occur in patients with neuroendocrine tumours of the pancreas?

Conclusion

The patient experienced a complete resolution of her myasthenia gravis-like syndrome after surgical removal of the neuroendocrine tumour.

Supporting Evidence

  • The patient had a neuroendocrine tumour in the pancreatic head.
  • She was negative for antibodies against acetylcholine receptors.
  • Her myasthenia gravis-like symptoms resolved after surgery.

Takeaway

A woman with a rare type of pancreatic tumour had symptoms of a disease called myasthenia gravis, but after doctors removed the tumour, she felt better and hasn't had symptoms for three years.

Methodology

The case involved imaging studies, fine-needle aspiration biopsy, and surgical enucleation of the pancreatic tumour.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

A 32-year-old woman with a history of thyroidectomy.

Digital Object Identifier (DOI)

10.1155/2011/309149

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