Epidemiological Features of Infantile Hypertrophic Pyloric Stenosis in Taiwanese Children: A Nation-Wide Analysis of Cases during 1997–2007
2011

Epidemiology of Infantile Hypertrophic Pyloric Stenosis in Taiwanese Children

Sample size: 1077 publication Evidence: moderate

Author Information

Author(s): Leong Mee-Mee, Chen Solomon Chih-Cheng, Hsieh Chih-Sung, Chin Yow-Yue, Tok Teck-Siang, Wu Shu-Fen, Peng Ching-Tien, Chen An-Chyi

Primary Institution: Pingtung Christian Hospital, China Medical University Hospital, Taipei Medical University

Hypothesis

To describe the epidemiological characteristics of infantile hypertrophic pyloric stenosis (IHPS) in ethnic Chinese children.

Conclusion

The incidence of IHPS in Taiwan is lower than in Caucasian populations, potentially due to breastfeeding and low maternal smoking rates.

Supporting Evidence

  • The annual incidence of IHPS ranged from 0.30 to 0.47 per 1,000 live births.
  • The overall male-to-female rate ratio was 4.30.
  • Breastfeeding rates increased significantly between 2002 and 2007.

Takeaway

This study looked at how many babies in Taiwan get a condition called IHPS, which makes it hard for them to eat. They found that fewer babies in Taiwan have this problem compared to babies in Western countries.

Methodology

Data was analyzed from the National Health Insurance claims database for children diagnosed with IHPS and who underwent pyloromyotomy between 1997 and 2007.

Potential Biases

Potential bias due to reliance on health insurance claims data.

Limitations

The study is based on secondary data analysis and lacks detailed information on maternal smoking rates.

Participant Demographics

1077 infants under one year of age, including 889 boys and 188 girls.

Statistical Information

P-Value

0.025

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0019404

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