Community-based trial of screening for Chlamydia to prevent pelvic inflammatory disease
Author Information
Author(s): Pippa Oakeshott, Sally Kerry, Helen Atherton, Adamma Aghaizu, Sima Hay, David Taylor-Robinson, Ian Simms, Phillip Hay
Primary Institution: St George's, University of London
Hypothesis
Does screening and treatment of chlamydial infection reduce the incidence of pelvic inflammatory disease (PID) over 12 months?
Conclusion
The trial aims to determine if screening for chlamydial infection can reduce the incidence of PID in young women.
Supporting Evidence
- Pelvic inflammatory disease (PID) can lead to infertility and chronic pain.
- Chlamydia trachomatis is a significant cause of PID.
- The study aims to provide new information on the effectiveness of chlamydia screening.
Takeaway
This study is trying to see if testing young women for a common infection can help prevent serious health problems later.
Methodology
Randomised controlled trial with follow-up after 12 months, involving self-administered vaginal swabs and questionnaires.
Potential Biases
Potential bias in follow-up due to knowledge of group assignment by some researchers.
Limitations
Recruitment was more difficult than anticipated, leading to an extended recruitment period.
Participant Demographics
Sexually active female students aged ≤ 27 years from 20 universities in Greater London.
Digital Object Identifier (DOI)
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