The Surveillance of Vero Cytotoxin-Producing Escherichia coli O157 in Wales, 1990 to 1998
1999

Surveillance of Vero Cytotoxin-Producing E. coli O157 in Wales (1990-1998)

Sample size: 415 publication Evidence: high

Author Information

Author(s): Rachel M. Chalmers, Sharon M. Parry, Roland L. Salmon, Robert M.M. Smith, Geraldine A. Willshaw, Tom Cheasty

Primary Institution: Public Health Laboratory Service Communicable Disease Surveillance Centre, Cardiff, United Kingdom

Conclusion

The incidence of VTEC O157 in Wales has remained stable over the years, with a mean of 1.6 cases per 100,000 population.

Supporting Evidence

  • From 1990 through 1998, 415 cases of VTEC O157 were reported in Wales.
  • The annual incidence remained stable at a mean of 1.6 cases per 100,000 population.
  • 49.9% of the patients were males, and the highest incidence was in children younger than 5 years.
  • Diarrhea was reported in 81.7% of cases, with 46.3% having blood in the stool.
  • 17.8% of cases were part of outbreaks, while 82.2% were sporadic.
  • Only one death was reported during the study period due to the infection.

Takeaway

This study looked at how many people got sick from a specific germ in Wales over 9 years, and it found that the number of cases stayed about the same each year.

Methodology

Population-based surveillance was conducted, testing all first-time acute-phase fecal specimens for VTEC O157.

Limitations

The study may not capture all cases as it relies on laboratory submissions and may miss asymptomatic cases.

Participant Demographics

Participants included 415 patients aged 3 months to 89 years, with a mean age of 25 years, and the highest incidence was in children under 5 years.

Statistical Information

Confidence Interval

95% CI calculated for various age-specific rates and symptoms.

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