Concomitant sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease) and diffuse large B-cell lymphoma: a case report
2008
Case of Rosai-Dorfman Disease and Lymphoma
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Moore James C, Zhao Xiaohui, Nelson Edward L
Primary Institution: University of California at Irvine, School of Medicine
Conclusion
The presence of Rosai-Dorfman Disease with significant lymphadenopathy should prompt clinicians to consider the possibility of concurrent non-Hodgkin's lymphoma.
Supporting Evidence
- Rosai-Dorfman Disease is a rare and benign condition that can mimic cancer.
- This case is one of the few documented instances of Rosai-Dorfman Disease occurring simultaneously with lymphoma.
- The patient experienced significant symptoms including weight loss and abdominal discomfort.
Takeaway
This study talks about a patient who had a rare disease called Rosai-Dorfman Disease along with a type of cancer called lymphoma, which made her very sick.
Methodology
The case was presented through clinical examination, imaging studies, and histological analysis.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
A 33-year-old Hispanic female with no significant past medical history.
Digital Object Identifier (DOI)
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