Serum Calcium Levels and Cardiometabolic Risk Factors
Author Information
Author(s): Guessous Idris, Bonny Olivier, Paccaud Fred, Mooser Vincent, Waeber Gérard, Vollenweider Peter, Bochud Murielle
Primary Institution: University of Lausanne, Lausanne, Switzerland
Hypothesis
What is the association between serum calcium levels and cardiometabolic risk factors in a general adult population?
Conclusion
Serum calcium levels are associated with both the metabolic syndrome and non-conventional cardiometabolic risk factors, particularly those related to oxidative stress.
Supporting Evidence
- Serum calcium levels increased with the number of metabolic syndrome components.
- Positive associations were found between serum calcium and oxidative stress markers like uric acid and homocysteine.
- Adiponectin showed a strong negative association with serum calcium levels.
Takeaway
This study found that higher levels of calcium in the blood might be linked to health issues like high blood pressure and diabetes, especially through factors that cause stress in the body.
Methodology
The study analyzed albumin-corrected serum calcium levels in relation to various cardiometabolic risk factors using multivariable regression in a population-based sample.
Potential Biases
Participants included in the analysis differed from the overall cohort, which may affect the generalizability of the findings.
Limitations
The study did not include vitamin D or parathyroid hormone levels, and the cross-sectional design limits causal inferences.
Participant Demographics
Caucasian adults aged 35 to 75 years from Lausanne, Switzerland.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website