Cognitive and academic outcome following cranial irradiation and chemotherapy in children: a longitudinal study
2000

Cognitive and academic outcomes in children after cancer treatment

Sample size: 89 publication Evidence: moderate

Author Information

Author(s): Anderson V A, Godber T, Smibert E, Weiskop S, Ekert H

Primary Institution: University of Melbourne

Hypothesis

Cranial irradiation and chemotherapy in children are associated with neurobehavioural deficits over time.

Conclusion

Children treated with cranial irradiation and chemotherapy showed cumulative deficits in non-verbal and information processing skills, while some literacy skills improved with educational intervention.

Supporting Evidence

  • Group 1, treated with cranial irradiation and chemotherapy, had the poorest results in intellectual abilities.
  • Comparison groups showed stable or improved abilities over time.
  • Educational intervention was linked to progress in literacy skills for Group 1.

Takeaway

Kids who had brain treatment for cancer might struggle with certain thinking skills as they grow, but they can get better at reading with help.

Methodology

The study used a longitudinal design to evaluate intellectual and educational abilities in three groups of children over time.

Limitations

The study did not include children with pre-existing neurological, developmental, or psychiatric disorders.

Participant Demographics

Children aged 7–13 years, with two groups having received different cancer treatments and one group being healthy.

Digital Object Identifier (DOI)

10.1054/bjoc.1999.0912

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication