Antimicrobial Resistance in Diabetic Women with UTIs
Author Information
Author(s): Hamdan Ahmad, AbuHaweeleh Mohannad N., Al-Qassem Leena, Kashkoul Amira, Alremawi Izzaldin, Hussain Umna, Khan Sara, ElBadway Menatalla M. S., Chivese Tawanda, Farooqui Habib H., Zughaier Susu M.
Primary Institution: College of Medicine, QU Health, Qatar University, Doha, Qatar
Hypothesis
This study investigates the prevalence of antimicrobial resistance (AMR) among women with urinary tract infections (UTIs) and its association with diabetes status.
Conclusion
The study found that women with diabetes had higher rates of antimicrobial resistance compared to those without diabetes.
Supporting Evidence
- AMR prevalence was 35.7% among women with diabetes and 21.3% among those without.
- Complicated diabetes was associated with 54% higher odds of developing AMR.
- An increased number of prescribed antibiotics was linked to higher odds of AMR.
Takeaway
Women with diabetes are more likely to have infections that don't respond to antibiotics, making it harder to treat their urinary tract infections.
Methodology
The study used a cross-sectional cohort analysis of data from the Physionet database, focusing on female participants treated for UTIs.
Potential Biases
The study could not investigate specific pathogens due to lack of comprehensive data, which may affect the interpretation of AMR patterns.
Limitations
The study's findings may not be generalizable due to its restriction to participants from specific hospitals in the Northeast USA.
Participant Demographics
The mean age was 52 years for women without diabetes and 68 years for those with diabetes; 72% of participants were of white ethnicity.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI 1.08–1.21 for uncomplicated diabetes; 95% CI 1.45–1.64 for complicated diabetes
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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