METANNOGEN: A Tool for Metabolic Network Reconstruction
Author Information
Author(s): Gille Christoph, Hoffmann Sabrina, Holzhütter Hermann-Georg
Primary Institution: Institute of Biochemistry Charité, Medical Faculty of the Humboldt University
Hypothesis
How can we effectively compile biochemical reactions to reconstruct metabolic networks?
Conclusion
METANNOGEN is a flexible tool to manage information for the design of metabolic networks.
Supporting Evidence
- METANNOGEN allows users to compile and manage biochemical reactions for metabolic network modeling.
- The program can export data in SBML format for further analysis.
- It provides links to various databases for additional information on reactions.
Takeaway
METANNOGEN helps scientists organize and manage data about biochemical reactions to build models of how cells work.
Methodology
The program uses the KEGG database to select, edit, and store biochemical reactions, allowing for manual entry of reactions not in KEGG.
Limitations
Users must manually enter reactions not contained in KEGG, and the program currently cannot perform consistency checks on the network.
Digital Object Identifier (DOI)
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