A Scanning Electron Microscopy Atlas of Normal and Malignant Leukocytes
1993

Scanning Electron Microscopy Atlas of Leukocytes

publication Evidence: low

Author Information

Author(s): A. Polliack, G. Lambertenghi-Deliliers, D. Soligo, D.H. Wright

Conclusion

The atlas shows that scanning electron microscopy has limited diagnostic value in haematopathology due to the lack of discriminatory surface morphologies in normal and malignant lymphocytes.

Supporting Evidence

  • Scanning electron microscopy images have limited diagnostic value in haematopathology.
  • Normal and neoplastic lymphocytes show little variation in surface morphology.
  • Artefacts from preparative procedures can mislead interpretations of cell surfaces.
  • The atlas does not effectively combine surface morphology with immunohistochemistry.
  • The illustrations do not correlate well with surface structures.

Takeaway

This book shows pictures of blood cells, but it doesn't help doctors tell the difference between healthy and sick cells.

Methodology

The atlas includes scanning electron microscopy images and discusses techniques for reducing artefacts.

Limitations

The atlas lacks valuable content for haematopathologists and researchers, making it a poor investment.

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