Aloe vera gel relieves cadmium triggered hepatic injury via antioxidative, anti-inflammatory, and anti-apoptotic routes
2024
Aloe Vera Gel Helps Protect the Liver from Cadmium Damage
Sample size: 40
publication
10 minutes
Evidence: high
Author Information
Author(s): Hassan Rasha E., Saleh Eman M., Hamdy Germine M.
Primary Institution: Ain Shams University
Hypothesis
Can Aloe vera gel mitigate liver injury caused by cadmium exposure?
Conclusion
Aloe vera gel has a significant protective effect against liver injury induced by cadmium exposure.
Supporting Evidence
- Aloe vera gel significantly reduced cadmium levels in the liver.
- Administration of Aloe vera gel improved oxidative stress markers in the liver.
- Aloe vera gel modulated inflammatory and apoptotic gene expressions.
- Rats treated with Aloe vera gel showed lower levels of liver damage indicators.
Takeaway
Aloe vera gel can help keep your liver healthy even when it gets hurt by bad stuff like cadmium.
Methodology
The study involved 40 Wistar male rats divided into four groups, with one group receiving Aloe vera gel and another group receiving cadmium chloride to assess liver damage.
Limitations
The study was conducted on rats, and results may not directly translate to humans.
Participant Demographics
Forty adult male Wistar rats, aged 10-12 weeks.
Statistical Information
P-Value
p ≤ 0.001
Statistical Significance
p ≤ 0.001
Digital Object Identifier (DOI)
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